Mammaglobin (31A5) Rabbit Monoclonal

Mammaglobin (10 kDa) is a breast-associated glycoprotein distantly related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin mRNA is present in high levels in human breast cancer cell lines, which has been shown to be a sensitive marker of breast cancer1,2,3. When combined with other breast-restricted markers such as GCDFP-15, an overall sensitivity for breast carcinoma of 84% has been achieved4. Anti-Mammaglobin can also be used to determine breast origin in the setting of metastatic carcinoma5,6.

  • Reactivity: paraffin
  • Visualization: cytoplasmic
  • Control: breast carcinoma
  • Isotype: IgG
  • Dilution Range: 1:100-1:500*
  1. Watson MA, et al. Cancer Research. 1999; 59:3028-3031.
  2. Fleming TP. Ann N Y Acad Sci. 2000; 923:78-89.
  3. Han JH, et al. Arch Pathol Lab Med. 2003; 127:1330-1334.
  4. Bhargava R, et al. Am J Clin Pathol. 2007; 127:103-13.
  5. Sasak E, et al. Mod Pathol. 2007; 20:208-14.
  6. Wang Z, et al. Int J Clin Exp Pathol. 2009; 2:384-9.

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Category: Antibody